Roger Knapp was an American DEA agent, who was stationed in Guadalajara, Mexico under James Kuykendall.

In the early 80s, his house and car were shot up by Mexican DFS agents as a warning to stay away from investigating the Guadalajara cartel. He was shortly rotated back home, but was called back after fellow agent Enrique Camarena Salazar's abduction by the cartel. He was one of the several agents who tried to unsuccessfully arrest cartel leader Rafael Caro Quintero before the latter could flee Mexico.

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